In 1846, a revolution directed by James Fazy, reverses the government of the Restoration and establishes the constitution which still governs the canton.
During the XIX E century and the beginning of the XX E century, Geneva accommodates many political refugees; most famous is Lénine, which remained there of 1903 to 1905 and in 1908.
According to the ideas of the Genevese Henry Dunant, the International committee of the Red Cross is created in 1864, first of the international institutions which the city will shelter.
The international mission of Geneva continues after the First World War, when it is selected like sits of the League of Nations, devancière of the United Nations Organization. Geneva remains the seat of its European office; several tens of other international institutions reside there, among which one can quote the International organization of Work (OIT), General Agreement on Tariffs and Trade (GATT), the World Health Organization (WHO), the European Organization for the nuclear research (CERN) and the World Council of Churches (COE).